⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2005545 | 0.79 | — | — | |
| SCHEMBL11159088 | 0.74 | ALDH1A1 (0.58) | — | |
| Ammonia Solution, Strong SCHEMBL28914391 | 0.67 | — | — | |
| SCHEMBL2444640 | 0.67 | — | — | |
| SCHEMBL29061272 | 0.65 | — | — | |
| SCHEMBL3643462 | 0.65 | — | — | |
| SCHEMBL14332206 | 0.64 | — | — | |
| SCHEMBL2438019 | 0.64 | — | — | |
| SCHEMBL28609350 | 0.63 | — | — | |
| SCHEMBL28611936 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 304 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666866-B2 | Antithrombotic diamides | ELI LILLY AND COMPANY (US) | 2010-02-23 | — | — | US | claimed |
| EP-1819693-B1 | ANTITHROMBOTIC DIAMIDES | LILLY CO ELI (US) | 2009-08-26 | — | — | EP | claimed |
| US-20090062271-A1 | Antithrombotic Diamides | ELI LILLY AND COMPANY (US) | 2009-03-05 | — | — | US | claimed |
| EP-1819693-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2007-08-22 | — | — | EP | claimed |
| WO-2006057868-A1 | ANTITHROMBOTIC DIAMIDES | ELI LILLY AND COMPANY (US) | 2006-06-01 | — | — | WO | claimed |
| US-20040260084-A1 | Novel c-3 s/o-and s/n formaldehe acetal derivatives of cephalosporins and their use as antibotics | PFAENDLER HANS R (DE) | 2004-12-23 | — | — | US | claimed |
| EP-0548338-B1 | PROCESS FOR THE PREPARATION OF CEPHALOSPORINS INTERMEDIATES | ANTIBIOTICOS SPA (IT) | 1996-10-23 | — | — | EP | claimed |
| EP-0333174-B1 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0382411-B1 | Delivery of cytotoxic agents | LILLY CO ELI (US) | 1994-12-07 | — | — | EP | claimed |
| WO-1994001137-A1 | METHOD FOR DELIVERY OF CYTOTOXIC AGENTS AND COMPONENTS THEREOF | HYBRITECH INCORPORATED (US) | 1994-01-20 | — | — | WO | claimed |
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | claimed |
| US-4144333-A | Monocyclic beta-lactams with antibacterial activity | SMITHKLINE CORPORATION (US) | 1979-03-13 | — | — | US | claimed |
| EP-0000645-A1 | Isopenicillins, processes for their preparation, and compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-02-07 | — | — | EP | claimed |
| US-4122086-A | Isopenicillins | SMITHKLINE CORPORATION (US) | 1978-10-24 | — | — | US | claimed |
| US-4053286-A | ACYLATION | MERCK & CO., INC. (US) | 1977-10-11 | — | — | US | claimed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | claimed |
| US-4009159-A | PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1977-02-22 | — | — | US | claimed |
| US-3972774-A | BY AN ESTERASE ENZYME FROM BACILLUS | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | claimed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | claimed |
| US-3943126-A | Process for acylating a 7-aminocephalosporin | ELI LILLY AND COMPANY (US) | 1976-03-09 | — | — | US | claimed |