Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19949594 | 0.72 | CYP19A1 (0.67) | APPMAOBPTGS2CYP19A1MEN1 | |
| SCHEMBL19949595 | 0.72 | CYP19A1 (0.67) | APPMAOBPTGS2CYP19A1MEN1 | |
| SCHEMBL8543924 | 0.69 | CYP19A1 (0.67) | APPMAOBCYP19A1MEN1KMT2A | |
| SCHEMBL8543928 | 0.69 | CYP19A1 (0.67) | APPMAOBCYP19A1MEN1KMT2A | |
| SCHEMBL9828718 | 0.63 | PTGS2 (0.66) | PTGS2CYP19A1TLR9PTGS1MAPT | |
| SCHEMBL9828721 | 0.63 | PTGS2 (0.66) | PTGS2CYP19A1TLR9PTGS1MAPT | |
| SCHEMBL14306002 | 0.62 | KRAS (0.65) | MAOBPTGS2CYP19A1MEN1KMT2A | |
| SCHEMBL31527932 | 0.62 | NPC1 (0.61) | PTGS2CYP19A1MEN1KMT2ANPC1 | |
| SCHEMBL14249195 | 0.62 | KRAS (0.65) | MAOBPTGS2CYP19A1MEN1KMT2A | |
| SCHEMBL10481633 | 0.60 | PTGS2 (0.72) | APPPTGS2CYP19A1TLR9PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053240-A1 | PEPTIDOMIMETICS AND METHODS OF USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2018-03-22 | — | — | WO | disclosed |