Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19978136 | 0.75 | PDK2 (0.31) | PDK2 | |
| SCHEMBL24933869 | 0.60 | PDK2 (0.41) | TSHRACHEPDK2 | |
| SCHEMBL19113478 | 0.59 | PDK2 (0.56) | TSHRACHEPDK2 | |
| SCHEMBL24484211 | 0.59 | PDE7A (0.43) | TSHRACHEPDK2 | |
| O-Xylene SCHEMBL28634943 | 0.59 | TSHR (0.77) | TSHRACHE | |
| SCHEMBL1627657 | 0.59 | HTR2A (0.48) | TSHRACHEPDK2 | |
| SCHEMBL29392540 | 0.59 | HTR2A (0.48) | TSHRACHEPDK2 | |
| SCHEMBL22044198 | 0.58 | PDK2 (0.52) | TSHRACHEPDK2 | |
| SCHEMBL24858844 | 0.57 | CA1 (0.39) | TSHRACHEPDK2 | |
| SCHEMBL11910663 | 0.57 | DRD1 (0.50) | TSHRACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079841-A1 | METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | LG CHEM, LTD. (KR) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079841-A1 | METALLOCENE SUPPORTED CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING THE SAME | PCBP1, SOD1, PCLAF | TSHR 4767/4885ACHE 2516/4885TP53 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.