Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979834 | 0.83 | POLB (0.47) | POLBKDM4EKMT2ATDP1HTT | |
| SCHEMBL19979837 | 0.82 | POLB (0.52) | POLBKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL19979826 | 0.80 | POLB (0.45) | POLBKDM4EKMT2ATDP1ALDH1A1 | |
| SCHEMBL19979827 | 0.80 | POLB (0.45) | POLBKDM4EKMT2ATDP1ALDH1A1 | |
| SCHEMBL19980213 | 0.79 | POLB (0.44) | POLBKDM4EGLAALDH1A1SMN1; SMN2 | |
| SCHEMBL11427377 | 0.75 | POLB (0.60) | POLBKDM4EKMT2ATDP1SMN1; SMN2 | |
| SCHEMBL19979962 | 0.74 | CYP1A2 (0.46) | POLBKDM4EL3MBTL1TDP1 | |
| SCHEMBL19979961 | 0.73 | MYC (0.53) | POLBKDM4EKMT2AL3MBTL1TDP1 | |
| SCHEMBL30597933 | 0.72 | MEN1 (0.56) | KDM4EKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL885409 | 0.72 | PARP1 (0.44) | KDM4EHTTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |