Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979961 | 0.82 | MYC (0.53) | CYP3A4CYP2C9POLBKDM4ETDP1 | |
| SCHEMBL885409 | 0.81 | PARP1 (0.44) | KDM4EMAPK10 | |
| SCHEMBL28642575 | 0.78 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL22717843 | 0.78 | TP53 (0.52) | KDM4ETDP1PKML3MBTL1HRH3 | |
| SCHEMBL30597933 | 0.76 | MEN1 (0.56) | CYP1A2CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL3435440 | 0.76 | OPRK1 (0.52) | POLBOPRK1 | |
| SCHEMBL28397648 | 0.74 | POLB (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL19979833 | 0.74 | POLB (0.53) | POLBKDM4ETDP1L3MBTL1 | |
| SCHEMBL15714564 | 0.74 | MYC (0.69) | POLBKDM4ETDP1PKML3MBTL1 | |
| SCHEMBL22421808 | 0.73 | CYP2A6 (0.45) | CYP1A2CYP2C9CYP2C19POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |