SCHEMBL19979902

SCHEMBL19979902

Cn1nnnc1NC(=O)c1ccc(C(F)(F)F)nc1-n1ccnn1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
HCRTR1 O43613 10/20 0.44
HCRTR2 O43614 9/20 0.44
LMNA P02545 1/20 0.36
SCN10A Q9Y5Y9 3/20 0.36
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19979963 0.88 POLB (0.47) POLBHCRTR1HCRTR2LMNASCN10A
SCHEMBL19980110 0.86 POLB (0.44) POLBHCRTR1HCRTR2LMNASCN10A
SCHEMBL19979903 0.85 POLB (0.47) POLBHCRTR1HCRTR2LMNASCN10A
SCHEMBL19980215 0.84 POLB (0.44) POLBLMNASCN10AGAA
SCHEMBL19980213 0.84 POLB (0.44) POLBHCRTR1HCRTR2LMNASCN10A
SCHEMBL19980132 0.84 POLB (0.44) POLBLMNASCN10AGAA
SCHEMBL19980107 0.83 POLB (0.43) POLBLMNASCN10AGAA
SCHEMBL19979920 0.83 POLB (0.43) POLBLMNASCN10AGAA
SCHEMBL19979874 0.83 POLB (0.43) POLBLMNASCN10AGAA
SCHEMBL19979901 0.83 POLB (0.43) POLBLMNASCN10AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050677-A1 HERBICIDAL PYRIDINES SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed