Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.34 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979920 | 0.90 | POLB (0.43) | POLBGAALMNACYP2C9CYP1A2 | |
| SCHEMBL19979927 | 0.89 | POLB (0.43) | POLBGAALMNACYP2C9CYP1A2 | |
| SCHEMBL19979924 | 0.89 | POLB (0.47) | POLBGAALMNACYP2C9CYP1A2 | |
| SCHEMBL19980216 | 0.88 | POLB (0.41) | POLBGAALMNAPDE4APDE4B | |
| SCHEMBL19980110 | 0.83 | POLB (0.44) | POLBGAALMNACYP2C9CYP1A2 | |
| SCHEMBL19979963 | 0.83 | POLB (0.47) | POLBGAALMNASCN10AKAT6A | |
| SCHEMBL19980213 | 0.83 | POLB (0.44) | POLBGAALMNACYP2C9CYP1A2 | |
| SCHEMBL19979902 | 0.83 | POLB (0.46) | POLBGAALMNASCN10A | |
| SCHEMBL19979903 | 0.83 | POLB (0.47) | POLBGAALMNACYP2C9CYP1A2 | |
| SCHEMBL19979874 | 0.82 | POLB (0.43) | POLBGAALMNACYP2C9CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |