Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980127 | 0.85 | POLB (0.44) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19980176 | 0.85 | POLB (0.44) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19980134 | 0.84 | POLB (0.43) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19980200 | 0.83 | POLB (0.47) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19980110 | 0.83 | POLB (0.44) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL147094 | 0.81 | LMNA (0.55) | POLBLMNACYP2C9GAARAB9A | |
| SCHEMBL19979903 | 0.81 | POLB (0.47) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19979874 | 0.80 | POLB (0.43) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19980199 | 0.80 | POLB (0.45) | POLBLMNACYP2C9CYP1A2HPGD | |
| SCHEMBL19980215 | 0.79 | POLB (0.44) | POLBLMNACYP2C9CYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |