Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29134998 | 1.00 | EP300 (0.43) | EP300GRIK1FAAHSOAT1MEN1 | |
| SCHEMBL5084408 | 0.91 | EP300 (0.55) | EP300FAAHSOAT1MEN1TP53 | |
| SCHEMBL639212 | 0.85 | — | — | |
| SCHEMBL11747745 | 0.85 | — | — | |
| SCHEMBL4280231 | 0.84 | EP300 (0.52) | EP300GRIK1FAAHSOAT1MEN1 | |
| Butane SCHEMBL6767216 | 0.83 | GRIK1 (0.38) | EP300GRIK1FAAHSOAT1MEN1 | |
| Hydrochloric Acid SCHEMBL6055071 | 0.83 | GRIK1 (0.38) | EP300GRIK1FAAHSOAT1MEN1 | |
| Chloromethane SCHEMBL18426109 | 0.81 | GRIK1 (0.37) | EP300GRIK1FAAHSOAT1MEN1 | |
| SCHEMBL180918 | 0.79 | EP300 (0.42) | EP300GRIK1FAAHSOAT1MEN1 | |
| SCHEMBL5831469 | 0.79 | EP300 (0.47) | EP300GRIK1FAAHSOAT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375780-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2020-06-03 | — | — | EP | disclosed |
| EP-3542193-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | Novartis AG (CH) | 2019-09-25 | — | — | EP | disclosed |
| US-20180141293-A1 | METHOD FOR MAKING OPHTHALMIC LENSES | ALCON INC. (CH) | 2018-05-24 | — | — | US | disclosed |
| EP-2956452-B1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE IP DEV LTD (GB) | 2018-03-21 | — | — | EP | disclosed |