Butane

Butane

SCHEMBL6767216

CCC/C=C(\N)C(N)=O.CCCC

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
FAAH O00519 3/20 0.35
BACE1 P56817 1/20 0.35
SOAT1 P35610 2/20 0.34
MEN1 O00255 1/20 0.34
TP53 P04637 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CNR1 P21554 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
KDM4E B2RXH2 2/20 0.31
EP300 Q09472 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL639212 0.97
SCHEMBL11747745 0.97
Hydrochloric Acid SCHEMBL6055071 0.95 GRIK1 (0.38) GRIK1GRIK2FAAHBACE1SOAT1
Chloromethane SCHEMBL18426109 0.93 GRIK1 (0.37) GRIK1GRIK2FAAHBACE1SOAT1
SCHEMBL29134998 0.83 EP300 (0.43) GRIK1FAAHSOAT1MEN1TP53
SCHEMBL19980211 0.83 EP300 (0.43) GRIK1FAAHSOAT1MEN1TP53
Butane SCHEMBL9158346 0.83 GRIK1 (0.46) GRIK1GRIK2FAAHBACE1SOAT1
SCHEMBL3293228 0.80
SCHEMBL1275230 0.80
SCHEMBL5084408 0.79 EP300 (0.55) FAAHSOAT1MEN1TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040250354-A1 Method for treating surfaces of textiles and non-textiles, in such a way as to stimulate the detachment of dirt BASF AKTIENGESELLSCHAFT (DE) 2004-12-16 US disclosed