Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP19 | O94966 | 2/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980708 | 0.92 | OPRM1 (0.48) | OPRM1OPRK1OPRL1KDM4CCNR1 | |
| SCHEMBL30576599 | 0.92 | MEN1 (0.33) | OPRM1OPRK1OPRL1PTGDR2MEN1 | |
| SCHEMBL19972512 | 0.92 | MEN1 (0.33) | OPRM1OPRK1OPRL1PTGDR2MEN1 | |
| SCHEMBL19972706 | 0.91 | OPRM1 (0.41) | OPRM1OPRK1OPRL1KDM4CCNR1 | |
| SCHEMBL19972588 | 0.91 | PIM2 (0.32) | OPRM1OPRK1OPRL1PTGDR2CCNT1 | |
| SCHEMBL30524053 | 0.90 | MEN1 (0.42) | OPRM1OPRK1OPRL1KDM4CPTGDR2 | |
| SCHEMBL19972591 | 0.90 | MEN1 (0.42) | OPRM1OPRK1OPRL1KDM4CPTGDR2 | |
| SCHEMBL26005930 | 0.90 | OPRM1 (0.32) | OPRM1OPRK1OPRL1PTGDR2MEN1 | |
| SCHEMBL19980719 | 0.90 | OPRM1 (0.45) | OPRM1OPRK1OPRL1KDM4C | |
| SCHEMBL19972620 | 0.89 | PTGDR2 (0.31) | KDM4CPTGDR2CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053267-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |