SCHEMBL1998078

SCHEMBL1998078

CCCCC(=O)Oc1c(F)cccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
RECQL P46063 1/20 0.50
POLM Q9NP87 1/20 0.43
POLK Q9UBT6 1/20 0.43
POLL Q9UGP5 1/20 0.43
POLH Q9Y253 1/20 0.43
HTR7 P34969 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.39
FAAH O00519 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
NLRP3 Q96P20 1/20 0.38
MIF P14174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7849303 0.91 IAPP (0.46) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL15559073 0.91 KMT2A (0.56) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL1993937 0.89 KMT2A (0.43) KMT2AKDM4EMEN1RECQLSMN1; SMN2
SCHEMBL29009795 0.89 KDM4E (0.44) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL31409726 0.86 KMT2A (0.41) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL15548594 0.86 POLM (0.53) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL28305792 0.85 TSHR (0.49) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL31409714 0.85 KMT2A (0.40) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL1999176 0.85 KMT2A (0.45) KMT2AKDM4EMEN1RECQLPOLM
SCHEMBL15548828 0.85 POLM (0.55) KMT2AKDM4EMEN1RECQLPOLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
CN-116209433-A Small molecule albumin binding agents 俄勒冈健康科学大学 2023-06-02 CN disclosed
EP-3609870-A1 SUBSTITUTED N-ARYLETHYL-2-AMINOQUINOLINE-4-CARBOXAMIDES AND USE THEREOF Bayer Aktiengesellschaft (DE) 2020-02-19 EP disclosed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed