SCHEMBL1999176

SCHEMBL1999176

CCCCC(=O)Oc1c(F)ccc(F)c1F

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
RECQL P46063 1/20 0.45
HTR7 P34969 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
HPGD P15428 2/20 0.40
EPHX2 P34913 1/20 0.38
ALOX15 P16050 1/20 0.38
MIF P14174 1/20 0.37
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
POLM Q9NP87 1/20 0.36
POLK Q9UBT6 1/20 0.36
POLL Q9UGP5 1/20 0.36
POLH Q9Y253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1996675 0.90 BCL9 (0.41) KMT2AKDM4EMEN1RECQLEPHX2
SCHEMBL1998098 0.86 KMT2A (0.44) KMT2AKDM4EMEN1RECQLHTR7
SCHEMBL1998078 0.85 KMT2A (0.50) KMT2AKDM4EMEN1RECQLHTR7
SCHEMBL1998865 0.82 ESR1 (0.42) KMT2ARECQLSMN1; SMN2ALOX15CES2
SCHEMBL1997072 0.82 MEN1 (0.45) KMT2AKDM4EMEN1RECQLHTR7
SCHEMBL1996406 0.82 KMT2A (0.51) KMT2AKDM4EMEN1RECQLHTR7
SCHEMBL28506184 0.81 ALOX15 (0.46) KMT2AKDM4EMEN1RECQLSMN1; SMN2
SCHEMBL15159286 0.81 SMN1; SMN2 (0.44) KMT2AKDM4EMEN1RECQLHTR7
SCHEMBL15236082 0.80 DGKA (0.46) KMT2ASMN1; SMN2ALOX15POLMPOLK
SCHEMBL27239124 0.80 DGKA (0.46) KMT2ASMN1; SMN2ALOX15POLMPOLK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US disclosed
CN-102186921-B Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2014-01-15 CN disclosed
EP-2338935-B1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS CO LTD (JP) 2012-12-12 EP disclosed
CN-102186921-A Fluorine-containing copolymer composition and process for production thereof ASAHI GLASS CO LTD 2011-09-14 CN disclosed
US-20110172336-A1 FLUOROCOPOLYMER COMPOSITION AND ITS PRODUCTION PROCESS ASAHI GLASS COMPANY, LIMITED (JP) 2011-07-14 US disclosed
EP-2338935-A1 FLUORINE-CONTAINING COPOLYMER COMPOSITION AND PROCESS FOR PRODUCTION THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2011-06-29 EP disclosed