Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | TACR2 | P21452 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148237 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL3721699 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL9640921 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL2145358 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL27647 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL868803 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL29011 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL151264 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL153908 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A | |
| SCHEMBL9789340 | 0.88 | DRD2 (0.56) | DRD2DRD3TAAR1ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759898-B2 | Fused thiophene-arylthiadiazole polymers, methods of making such polymers, and uses thereof | CORNING INCORPORATED (US) | 2020-09-01 | — | — | US | disclosed |
| US-20180079858-A1 | FUSED THIOPHENE-ARYLTHIADIAZOLE POLYMERS, METHODS OF MAKING SUCH POLYMERS, AND USES THEREOF | CORNING INCORPORATED | 2018-03-22 | — | — | US | disclosed |