Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984852 | 0.79 | KDM4E (0.37) | KDM4EALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL15504860 | 0.71 | TDP1 (0.51) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19981162 | 0.71 | POLB (0.56) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL11798568 | 0.70 | TDP1 (0.58) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL12612104 | 0.67 | TDP1 (0.54) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19981321 | 0.66 | KDM4E (0.52) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL9965991 | 0.65 | NPC1 (0.54) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19981338 | 0.64 | POLB (0.40) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19981343 | 0.64 | KDM4E (0.52) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL19981268 | 0.63 | POLB (0.43) | TDP1KDM4EPOLBL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |