SCHEMBL19981440

SCHEMBL19981440

CCS(=O)(=O)c1ccc(Cl)nc1-c1ncc(Br)n1C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP2D6 P10635 1/20 0.32
COMT P21964 1/20 0.32
MAPT P10636 1/20 0.31
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21895329 0.78 HPGD (0.33) DDR1ALDH1A1
SCHEMBL19981221 0.75 DDR1 (0.31) DDR1
SCHEMBL19762754 0.75 MEN1 (0.35) ALDH1A1CYP11B2
SCHEMBL18854924 0.75 BRD4 (0.36) DDR1ALDH1A1CYP2D6CYP11B2
SCHEMBL18423759 0.75 HSD17B10 (0.38) ALDH1A1MAPT
SCHEMBL24414192 0.74 DDR1 (0.32) DDR1COMT
SCHEMBL29653525 0.74 DDR1 (0.32) DDR1COMT
SCHEMBL21182219 0.73
SCHEMBL29308383 0.73
SCHEMBL17844037 0.71 POLB (0.44) DDR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2024-07-16 US disclosed
CN-109689630-B Diaryl azole compound and pest control agent 日本曹达株式会社 2022-06-03 CN disclosed
EP-3514146-B1 DIARYL- AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO (JP) 2022-03-16 EP disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2022-02-03 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism NIPPON SODA CO., LTD. (JP) 2021-11-23 US disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
EP-3514146-A1 DIARYL AZOLE COMPOUND AND PESTICIDE Nippon Soda Co., Ltd. (JP) 2019-07-24 EP disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM NIPPON SODA CO., LTD. (JP) 2019-06-20 US disclosed
CN-109689630-A Diaryl azole compound and pest control agent 日本曹达株式会社 2019-04-26 CN disclosed
WO-2018052035-A1 DIARYL AZOLE COMPOUND AND PESTICIDE 日本曹達株式会社 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220033384-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L DDR1 1096/4885ALDH1A1 1972/4885CYP2D6 210/4885
US-20190185459-A1 DIARYL-AZOLE COMPOUND AND FORMULATION FOR CONTROLLING HARMFUL ORGANISM CRY1, CRKL, CDC5L DDR1 1096/4885ALDH1A1 1972/4885CYP2D6 210/4885
US-12037326-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L DDR1 1096/4885ALDH1A1 1972/4885CYP2D6 210/4885
US-11180485-B2 Diaryl-azole compound and formulation for controlling harmful organism CRY1, CRKL, CDC5L DDR1 1096/4885ALDH1A1 1972/4885CYP2D6 210/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.