Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443760 | 0.83 | MEN1 (0.41) | SMN1; SMN2L3MBTL3L3MBTL1LMNAKDM4E | |
| SCHEMBL14417614 | 0.82 | GAA (0.38) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15871546 | 0.81 | SMN1; SMN2 (0.34) | SMN1; SMN2L3MBTL3L3MBTL1LMNAKDM4E | |
| SCHEMBL22388964 | 0.79 | MEN1 (0.34) | SMN1; SMN2L3MBTL3L3MBTL1LMNAKDM4E | |
| SCHEMBL19981539 | 0.73 | CHRM2 (0.33) | L3MBTL3L3MBTL1CHRM2CHRM1CHRM3 | |
| SCHEMBL14995421 | 0.72 | L3MBTL3 (0.42) | SMN1; SMN2L3MBTL3L3MBTL1LMNAKDM4E | |
| SCHEMBL16877830 | 0.71 | — | — | |
| SCHEMBL14862483 | 0.71 | SMN1; SMN2 (0.50) | SMN1; SMN2L3MBTL3L3MBTL1OPRL1ALDH1A1 | |
| SCHEMBL25775999 | 0.71 | — | — | |
| SCHEMBL12706415 | 0.71 | SMN1; SMN2 (0.40) | SMN1; SMN2L3MBTL3L3MBTL1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2788488-B1 | METHODS FOR TREATING PROGEROID LAMINOPATHIES USING OLIGONUCLEOTIDE ANALOGUES TARGETING HUMAN LMNA | SAREPTA THERAPEUTICS INC (US) | 2018-03-21 | — | — | EP | disclosed |