Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9984405 | 0.79 | BTK (0.48) | BTK | |
| SCHEMBL9985483 | 0.68 | BTK (0.48) | BTK | |
| SCHEMBL9984396 | 0.68 | BTK (0.47) | BTK | |
| SCHEMBL9984789 | 0.66 | BTK (0.43) | BTK | |
| SCHEMBL9984564 | 0.64 | BTK (0.41) | BTK | |
| SCHEMBL2532115 | 0.64 | BTK (0.41) | BTK | |
| SCHEMBL9985165 | 0.64 | BTK (0.41) | BTK | |
| SCHEMBL19981913 | 0.64 | NTRK1 (0.38) | BTK | |
| SCHEMBL2492181 | 0.63 | BTK (0.61) | BTK | |
| SCHEMBL2464623 | 0.63 | BTK (0.42) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2365970-B1 | PYRIDAZINONES AND THEIR USE AS BTK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2018-03-21 | — | — | EP | disclosed |