Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14308022 | 0.89 | CYP17A1 (0.38) | ESR1ESR2CYP17A1RIPK1CYP19A1 | |
| SCHEMBL13452656 | 0.79 | IDO1 (0.30) | — | |
| SCHEMBL21164691 | 0.75 | ESR1 (0.46) | ESR1ESR2CYP17A1RIPK1AR | |
| SCHEMBL25101398 | 0.74 | ESR1 (0.48) | ESR1ESR2CYP17A1RIPK1AR | |
| SCHEMBL19232109 | 0.74 | CNR2 (0.42) | ESR1ESR2RIPK1ARKCNN4 | |
| SCHEMBL6700733 | 0.72 | ESR1 (0.38) | ESR1ESR2CYP17A1RIPK1AR | |
| SCHEMBL19226355 | 0.72 | ALDH1A1 (0.49) | ESR1ESR2ARCYP19A1HTR7 | |
| SCHEMBL4284381 | 0.72 | ESR1 (0.38) | ESR1ESR2CYP17A1RIPK1AR | |
| SCHEMBL25634541 | 0.72 | NR3C2 (0.41) | KDM4E | |
| SCHEMBL14618158 | 0.72 | ESR1 (0.50) | ESR1ACHEALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2273966-B1 | USE OF ORGANO-MODIFIED SILOXANE BLOCK COPOLYMERS FOR PRODUCING COSMETIC COMPOSITIONS | EVONIK DEGUSSA GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |