Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TACR1 | P25103 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20111185 | 0.79 | POLB (0.36) | HPGDSMN1; SMN2CYP4F2CYP4A11POLB | |
| SCHEMBL20111175 | 0.79 | POLB (0.36) | HPGDSMN1; SMN2CYP4F2CYP4A11POLB | |
| SCHEMBL19982523 | 0.78 | KDM4E (0.34) | HPGDSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL20111171 | 0.73 | KMT2A (0.37) | HPGDSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL20111191 | 0.73 | KMT2A (0.37) | HPGDSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL20111184 | 0.73 | KMT2A (0.37) | HPGDSMN1; SMN2L3MBTL1ALDH1A1LMNA | |
| SCHEMBL19982455 | 0.72 | HPGD (0.30) | HPGDSMN1; SMN2 | |
| SCHEMBL20118877 | 0.71 | KDM4E (0.31) | SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL20118879 | 0.71 | KDM4E (0.31) | SMN1; SMN2ALDH1A1LMNAKMT2A | |
| SCHEMBL18716811 | 0.71 | KDM4E (0.31) | SMN1; SMN2ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296296-A1 | CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-03-21 | — | — | EP | disclosed |