Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19982604 | 0.78 | HPGD (0.33) | KMT2ATACR1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL19982402 | 0.73 | TLR4 (0.36) | KMT2AMEN1MAPK1MAPTL3MBTL1 | |
| SCHEMBL19982406 | 0.70 | TSHR (0.33) | KDM4EKMT2AMEN1MAPK1MAPT | |
| SCHEMBL20111184 | 0.67 | KMT2A (0.37) | KDM4EKMT2AMEN1MAPK1MAPT | |
| SCHEMBL20111191 | 0.67 | KMT2A (0.37) | KDM4EKMT2AMEN1MAPK1MAPT | |
| SCHEMBL20111171 | 0.67 | KMT2A (0.37) | KDM4EKMT2AMEN1MAPK1MAPT | |
| SCHEMBL20111175 | 0.58 | POLB (0.36) | KMT2AMEN1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL20111185 | 0.58 | POLB (0.36) | KMT2AMEN1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL20111186 | 0.57 | LMNA (0.34) | KDM4EKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL12812401 | 0.57 | MAPT (0.60) | KMT2AMEN1MAPK1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3296296-A1 | CYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-03-21 | — | — | EP | disclosed |