Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 13/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19986772 | 0.93 | SLC2A1 (0.42) | BCHEACHECHEK2GRIN1GRIN2B | |
| SCHEMBL19982657 | 0.92 | DRD4 (0.42) | BCHEACHECHEK2 | |
| SCHEMBL19986770 | 0.86 | BCHE (0.45) | BCHEACHECHEK2GRIN1GRIN2B | |
| SCHEMBL19970824 | 0.82 | BCHE (0.45) | BCHEACHECHEK2GRIN1GRIN2B | |
| SCHEMBL19986769 | 0.82 | DRD4 (0.45) | BCHEACHECHEK2 | |
| SCHEMBL19982584 | 0.81 | CHEK2 (0.46) | BCHEACHECHEK2 | |
| SCHEMBL19982651 | 0.81 | CYP1A2 (0.42) | BCHEACHECHEK2 | |
| SCHEMBL19982564 | 0.80 | SLC2A1 (0.42) | BCHEACHECHEK2GRIN1GRIN2B | |
| SCHEMBL19982656 | 0.79 | DRD4 (0.42) | BCHEACHECHEK2 | |
| SCHEMBL19970723 | 0.79 | CHEK2 (0.43) | BCHEACHECHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050771-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-22 | — | — | WO | disclosed |
| EP-3296297-A1 | BENZIMIDAZOL DERIVATIVES FOR TREATING FILOVIRUS INFECTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-03-21 | — | — | EP | disclosed |