Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 13/20 | 0.65 |
| ▸ | ERAP1 | Q9NZ08 | 13/20 | 0.65 |
| ▸ | LNPEP | Q9UIQ6 | 11/20 | 0.65 |
| ▸ | IL1RN | P18510 | 3/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.52 |
| ▸ | FCER2 | P06734 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17706116 | 0.91 | LTA4H (0.61) | ERAP2ERAP1LNPEPMMP3ANPEP | |
| Hydrochloric Acid SCHEMBL15634708 | 0.90 | LTA4H (0.60) | ERAP2ERAP1LNPEPMMP3ANPEP | |
| Hydrochloric Acid SCHEMBL15634706 | 0.90 | LTA4H (0.60) | ERAP2ERAP1LNPEPMMP3ANPEP | |
| SCHEMBL15581362 | 0.88 | ERAP2 (0.64) | ERAP2ERAP1LNPEPIL1RNMMP3 | |
| SCHEMBL14441431 | 0.88 | CTSC (0.51) | ERAP2ERAP1LNPEPIL1RNMMP3 | |
| SCHEMBL22130539 | 0.87 | ERAP2 (0.62) | ERAP2ERAP1LNPEPIL1RNMMP3 | |
| SCHEMBL15581384 | 0.87 | ERAP2 (0.55) | ERAP2ERAP1LNPEPMMP3LTA4H | |
| SCHEMBL2487473 | 0.86 | LTA4H (0.62) | ERAP2ERAP1LNPEPMMP3FCER2 | |
| SCHEMBL12057953 | 0.86 | LTA4H (0.62) | ERAP2ERAP1LNPEPMMP3FCER2 | |
| SCHEMBL12038997 | 0.86 | LTA4H (0.62) | ERAP2ERAP1LNPEPMMP3FCER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512835-B1 | A PROCESS FOR PURIFICATION OF CARFILZOMIB INTERMEDIATE | FRESENIUS KABI ONCOLOGY LTD (IN) | 2021-06-09 | — | — | EP | disclosed |
| WO-2018051237-A1 | A PROCESS FOR PURIFICATION OF CARFILZOMIB INTERMEDIATE | FRESENIUS KABI ONCOLOGY LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |