Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16281010 | 0.78 | TDP1 (0.51) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL19975535 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL19974721 | 0.74 | SMN1; SMN2 (0.43) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL19974974 | 0.71 | EPHX1 (0.42) | CTSKSMN1; SMN2TDP1ALDH1A1EPHX1 | |
| SCHEMBL19975124 | 0.71 | SMN1; SMN2 (0.41) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL19982747 | 0.71 | EPHX1 (0.45) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL13581 | 0.70 | EPHX1 (0.55) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL19652274 | 0.70 | EPHX1 (0.55) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 | |
| SCHEMBL21176387 | 0.70 | EPHX1 (0.44) | CTSKSMN1; SMN2TDP1ALDH1A1EPHX1 | |
| SCHEMBL12026402 | 0.69 | EPHX1 (0.52) | SMN1; SMN2TDP1ALDH1A1EPHX1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |