Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974721 | 0.85 | SMN1; SMN2 (0.43) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL19975535 | 0.84 | SMN1; SMN2 (0.43) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL19975124 | 0.82 | SMN1; SMN2 (0.41) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL16281010 | 0.79 | TDP1 (0.51) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL19974929 | 0.74 | METAP2 (0.48) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL19974786 | 0.73 | EPHX1 (0.46) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL19974914 | 0.73 | EPHX1 (0.46) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL7352599 | 0.73 | METAP2 (0.64) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL19975350 | 0.72 | EPHX1 (0.45) | EPHX1CA12CA1CA2MMP1 | |
| SCHEMBL21176177 | 0.72 | METAP2 (0.56) | EPHX1CA12CA1CA2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |