Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21176171 | 0.83 | KDM4E (0.44) | KDM4EPKMEPHX1GLSMEN1 | |
| SCHEMBL21176200 | 0.82 | KDM4E (0.45) | KDM4EPKMEPHX1GLSMEN1 | |
| SCHEMBL21176384 | 0.80 | KDM4E (0.46) | KDM4EPKMEPHX1GLSMEN1 | |
| SCHEMBL21183545 | 0.78 | KDM4E (0.45) | KDM4EPKMEPHX1GLSMEN1 | |
| SCHEMBL21176196 | 0.77 | KDM4E (0.47) | KDM4EPKMEPHX1GLSKMT2A | |
| SCHEMBL21176275 | 0.75 | NAMPT (0.38) | KDM4EPKMEPHX1GLSCTSS | |
| SCHEMBL21176247 | 0.75 | KDM4E (0.48) | KDM4EPKMEPHX1GLSKMT2A | |
| SCHEMBL19982898 | 0.74 | EPHX1 (0.35) | EPHX1CTSSCTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL19982734 | 0.72 | KDM4E (0.45) | KDM4EPKMEPHX1GLSCTSS | |
| SCHEMBL19652088 | 0.71 | KDM4E (0.60) | KDM4EPKMEPHX1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |