SCHEMBL19982898

SCHEMBL19982898

N#CC(C(O)C(=O)NCC1CCCCC1)N(C=O)CC1CC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.35
CTSK P43235 4/20 0.35
CTSL P07711 3/20 0.35
CTSB P07858 3/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP9 P14780 1/20 0.34
MMP8 P22894 1/20 0.34
CA9 Q16790 1/20 0.34
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP2D6 P10635 1/20 0.33
BCHE P06276 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 2/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19982900 0.84 HPGD (0.36) EPHX1CTSKCTSLCTSBTSHR
SCHEMBL19975400 0.81 SMN1; SMN2 (0.40) EPHX1CA12CA1CA2MMP1
SCHEMBL19974838 0.81 SMN1; SMN2 (0.40) EPHX1CA12CA1CA2MMP1
SCHEMBL19974951 0.74 CTSD (0.39) EPHX1CA12CA1CA2MMP1
SCHEMBL21183515 0.74 ALOX15 (0.40) EPHX1CA12CA1CA2MMP1
SCHEMBL19982894 0.74 KDM4E (0.42) EPHX1CTSKSMN1; SMN2ALDH1A1CTSS
SCHEMBL21176382 0.73 CTSD (0.33) SMN1; SMN2TDP1CYP3A4
SCHEMBL19975112 0.72 MEN1 (0.36) EPHX1TSHRSMN1; SMN2CYP2D6BCHE
SCHEMBL19974937 0.71 ALDH1A1 (0.34) EPHX1TSHRSMN1; SMN2CYP2D6BCHE
SCHEMBL19975106 0.71 EPHX1 (0.40) EPHX1CA12CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed