SCHEMBL19982903

SCHEMBL19982903

CC(C#N)C(NCC1CCOCC1)C(O)C(=O)NCC1CC1

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSS P25774 4/20 0.33
CNR2 P34972 3/20 0.33
CYP3A4 P08684 2/20 0.33
ALDH1A1 P00352 1/20 0.33
HTR4 Q13639 3/20 0.32
NAMPT P43490 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
BACE1 P56817 1/20 0.32
SCN9A Q15858 1/20 0.32
CTSD P07339 2/20 0.31
KMT2A Q03164 1/20 0.31
CYP2D6 P10635 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975367 0.86 NPC1 (0.34) CNR2CYP3A4HTR4NAMPTNPC1
SCHEMBL21176215 0.80 TDP1 (0.36) CNR2CYP3A4HTR4NPC1RAB9A
SCHEMBL21183504 0.76 NPC1 (0.33) CNR2HTR4NAMPTNPC1RAB9A
SCHEMBL19974829 0.74 TDP1 (0.40) ALDH1A1CTSDKMT2ACYP2D6
SCHEMBL19982704 0.74 ALDH1A1 (0.33) CNR2CYP3A4ALDH1A1NAMPTNPC1
SCHEMBL19974853 0.74 TDP1 (0.35) CNR2NAMPTNPC1RAB9ABACE1
SCHEMBL19982847 0.74 NAMPT (0.34) CYP3A4ALDH1A1NAMPT
SCHEMBL21183503 0.73 TSHR (0.33) NAMPTNPC1RAB9ABACE1CTSD
SCHEMBL9891788 0.72 BACE1 (0.41) CNR2CYP3A4HTR4NAMPTNPC1
SCHEMBL19975024 0.72 KMT2A (0.36) CNR2HTR4NPC1RAB9ABACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed