Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.46 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 7/20 | 0.39 |
| ▸ | CES1 | P23141 | 5/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 6/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069765 | 0.97 | CES2 (0.43) | CES2LPAR1LPAR3TSHRTHRB | |
| Hydrochloric Acid SCHEMBL27437749 | 0.94 | CES2 (0.41) | CES2LPAR1LPAR3TSHRTHRB | |
| Hydrochloric Acid SCHEMBL27435012 | 0.94 | CES2 (0.41) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL23139281 | 0.94 | CES2 (0.50) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL28301994 | 0.94 | CES2 (0.50) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL16171314 | 0.94 | CES2 (0.50) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL11867732 | 0.88 | TSHR (0.35) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL29691910 | 0.88 | CES2 (0.44) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL23014931 | 0.86 | CES2 (0.35) | CES2LPAR1LPAR3 | |
| SCHEMBL16925432 | 0.83 | CES2 (0.46) | CES2LPAR1LPAR3TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103983-A9 | FLUORENYLMETHYLOXYCARBONYL AND FLUORENYLMETHYLAMINOCARBONYL COMPOUNDS, PROTEIN CONJUGATES THEREOF, AND METHODS FOR THEIR USE | SUTRO BIOPHARMA, INC. (US) | 2022-06-09 | — | — | WO | disclosed |
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |