Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.30 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16418327 | 0.84 | — | — | |
| SCHEMBL27936225 | 0.79 | ALDH1A1 (0.44) | ALDH1A1TDP1TSHRCYP3A4CA2 | |
| SCHEMBL12169475 | 0.78 | MEN1 (0.34) | CYP3A4 | |
| SCHEMBL8053137 | 0.74 | — | — | |
| SCHEMBL804669 | 0.74 | MEN1 (0.42) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL30122685 | 0.73 | ALDH1A1 (0.39) | ALDH1A1TDP1TSHRCYP3A4CA2 | |
| SCHEMBL6558374 | 0.73 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCYP3A4 | |
| SCHEMBL27266656 | 0.73 | ALDH1A1 (0.31) | ALDH1A1TDP1 | |
| SCHEMBL28355881 | 0.72 | — | — | |
| SCHEMBL14981590 | 0.72 | MAPK1 (0.33) | ALDH1A1TDP1TSHRLPAR1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881394-B1 | CONDENSED RING HETEROCYCLIC COMPOUND | KYOWA HAKKO KIRIN CO LTD (JP) | 2018-03-21 | — | — | EP | disclosed |