Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.70 |
| ▸ | CTSL | P07711 | 4/20 | 0.64 |
| ▸ | CTSB | P07858 | 3/20 | 0.64 |
| ▸ | CTSH | P09668 | 3/20 | 0.64 |
| ▸ | CTSS | P25774 | 3/20 | 0.64 |
| ▸ | CTSF | Q9UBX1 | 2/20 | 0.64 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19983102 | 0.99 | CTSK (0.71) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL30716868 | 0.99 | CTSK (0.71) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL19983196 | 0.99 | CTSK (0.71) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL25658845 | 0.91 | CTSK (0.61) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL25658806 | 0.91 | CTSK (0.61) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL19982987 | 0.87 | CTSK (0.69) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL30716866 | 0.87 | CTSK (0.69) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL19983103 | 0.87 | CTSK (0.69) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL22292206 | 0.84 | CTSK (0.98) | CTSKCTSLCTSBCTSHCTSS | |
| SCHEMBL30716864 | 0.82 | CTSK (1.00) | CTSKCTSLCTSBCTSHCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018053353-A1 | KETONE INHIBITORS OF LYSINE GINGIPAIN | Cortexyme, Inc. (US) | 2018-03-22 | — | — | WO | disclosed |