SCHEMBL19983449

SCHEMBL19983449

CC(c1ccc2c(c1)OCO2)C(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
CYP2D6 P10635 2/20 0.49
CYP2C9 P11712 2/20 0.49
CYP2C19 P33261 2/20 0.49
TAAR1 Q96RJ0 2/20 0.49
SLC6A2 P23975 2/20 0.49
SLC6A3 Q01959 2/20 0.49
SLC6A4 P31645 1/20 0.49
PGR P06401 1/20 0.46
AR P10275 1/20 0.46
GABRA1 P14867 1/20 0.46
MAOA P21397 1/20 0.46
PDE4A P27815 1/20 0.46
KDR P35968 1/20 0.46
GABRB2 P47870 1/20 0.46
MAPK1 P28482 1/20 0.46
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
OGA O60502 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12626858 1.00 CYP1A2 (0.49) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL12569811 0.84 CYP1A2 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL13226837 0.84 CYP2D6 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL12404264 0.83 SLC6A2 (0.47) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL22854152 0.83 CYP2D6 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL29329632 0.83 CYP2D6 (0.48) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL21342600 0.82 CYP1A2 (0.47) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL12570228 0.81 TAAR1 (0.49) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL8927079 0.81 SLC6A2 (0.46) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL24489511 0.81 CYP3A4 (0.51) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12044968-B2 Protective film-forming composition having acetal structure and amide structure NISSAN CHEMICAL CORPORATION (JP) 2024-07-23 US disclosed
US-20220026806-A1 PROTECTIVE FILM-FORMING COMPOSITION HAVING ACETAL STRUCTURE AND AMIDE STRUCTURE NISSAN CHEMICAL CORPORATION (JP) 2022-01-27 US disclosed
WO-2018053313-A1 ADENOSINE ANALOGS AS METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER MEMORIAL SLOAN-KETTERING CANCER CENTER (US) 2018-03-22 WO disclosed