SCHEMBL8927079

SCHEMBL8927079

[CH2]C(c1ccc2c(c1)OCO2)C(C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 2/20 0.46
SLC6A3 Q01959 2/20 0.46
PGR P06401 1/20 0.46
AR P10275 1/20 0.46
GABRA1 P14867 1/20 0.46
MAOA P21397 1/20 0.46
PDE4A P27815 1/20 0.46
KDR P35968 1/20 0.46
GABRB2 P47870 1/20 0.46
CYP3A4 P08684 3/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
MAPK1 P28482 1/20 0.46
ACHE P22303 2/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
SMAD3 P84022 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12404264 0.83 SLC6A2 (0.47) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL12570228 0.81 TAAR1 (0.49) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL12626858 0.81 CYP1A2 (0.49) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL19983449 0.81 CYP1A2 (0.49) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL12569811 0.80 CYP1A2 (0.48) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL21342600 0.79 CYP1A2 (0.47) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL14218391 0.77 CYP1A2 (0.46) SLC6A2SLC6A3PGRARGABRA1
SCHEMBL24489511 0.77 CYP3A4 (0.51) SLC6A2SLC6A3CYP3A4CYP1A2CYP2D6
SCHEMBL13754486 0.77 CYP3A4 (0.51) SLC6A2SLC6A3CYP3A4CYP1A2CYP2D6
SCHEMBL7898797 0.76 CYP3A4 (0.54) SLC6A2SLC6A3PGRARGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691363-A CONTROLLING PHYTOPATHOGENIC FUNGI; APPLYING TO PLANT BEFORE PLANTING UNIROYAL CHEMICAL COMPANY, INC. (US) 1997-11-25 US disclosed
US-5574056-A CONTROLLING FUNGI ON PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-11-12 US disclosed
WO-1995029901-A1 FUNGICIDAL AZOLE DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. (US) 1995-11-09 WO disclosed