SCHEMBL19983756

SCHEMBL19983756

C=CCOC(=O)C1(C)CCCCC1=C(C#N)C#N

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTP4A3 O75365 2/20 0.31
PTP4A1 Q93096 2/20 0.31
PTP4A2 Q12974 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24091426 0.84 ALDH1A1 (0.37)
SCHEMBL21319246 0.82 ALDH1A1 (0.31)
SCHEMBL24091772 0.80 ALDH1A1 (0.38)
SCHEMBL14498565 0.78 ALDH1A1 (0.33)
SCHEMBL18101498 0.77 ALDH1A1 (0.33)
SCHEMBL23687221 0.74 ALDH1A1 (0.34)
SCHEMBL19973058 0.72 ALDH1A1 (0.31)
SCHEMBL7175708 0.71 CYP3A4 (0.38)
SCHEMBL21319095 0.71 ALDH1A1 (0.30)
SCHEMBL18101499 0.68 CYP3A4 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2024-01-25 US disclosed
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIV FLORIDA (US) 2019-09-05 US disclosed
WO-2018053322-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS SQLE, GGPS1, LSS PTP4A3 2793/4885PTP4A1 3197/4885PTP4A2 2833/4885
US-20190270700-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS SQLE, GGPS1, LSS PTP4A3 2724/4885PTP4A1 3206/4885PTP4A2 2775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.