Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619174 | 0.79 | MEN1 (0.45) | NR4A2MAPK8KMT2ALMNAMAPK1 | |
| SCHEMBL19984298 | 0.75 | NR4A2 (0.50) | NR4A2ERN1 | |
| SCHEMBL19983912 | 0.71 | NR4A2 (0.50) | NR4A2KMT2ALMNAALDH1A1 | |
| SCHEMBL16618580 | 0.67 | NR4A2 (0.50) | NR4A2KMT2ALMNAMAPK1POLB | |
| SCHEMBL19971506 | 0.66 | AKR1C3 (0.42) | KMT2ALMNAMETAP2ALDH1A1ERN1 | |
| SCHEMBL35210674 | 0.65 | NR4A2 (0.46) | NR4A2KMT2ALMNAMETAP2MAPT | |
| SCHEMBL2811920 | 0.65 | NR4A2 (0.58) | NR4A2 | |
| SCHEMBL19983804 | 0.64 | EPHX2 (0.37) | METAP2MAPT | |
| SCHEMBL22392835 | 0.63 | KCNQ3 (0.46) | KMT2ALMNAALDH1A1 | |
| SCHEMBL30421160 | 0.63 | KCNQ3 (0.46) | KMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052484-B1 | SULFONYLINDOLE DERIVATIVES AND METHOD FOR PREPARING THE SAME | DAE WOONG PHARMA (KR) | 2018-03-21 | — | — | EP | disclosed |