Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.62 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD1 | P21728 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903847 | 0.90 | ADRB2 (0.57) | ADRB2CHRM3CACNA1CADRB1 | |
| SCHEMBL20373394 | 0.90 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 | |
| SCHEMBL19903898 | 0.88 | ADRB2 (0.59) | ADRB2CHRM3 | |
| SCHEMBL14240818 | 0.85 | CHRM3 (0.76) | ADRB2CHRM3CACNA1CADRB1 | |
| SCHEMBL19903858 | 0.85 | ADRB2 (0.60) | ADRB2CHRM3 | |
| SCHEMBL19970974 | 0.85 | CHRM3 (0.87) | ADRB2CHRM3CACNA1C | |
| SCHEMBL16579657 | 0.85 | CHRM3 (0.87) | ADRB2CHRM3CACNA1C | |
| SCHEMBL15786721 | 0.85 | CHRM3 (0.87) | ADRB2CHRM3CACNA1C | |
| SCHEMBL16579656 | 0.85 | CHRM3 (0.87) | ADRB2CHRM3CACNA1C | |
| SCHEMBL19970975 | 0.85 | CHRM3 (0.87) | ADRB2CHRM3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928889-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-03-21 | — | — | EP | disclosed |