Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903844 | 0.85 | ADRB2 (0.54) | ADRB2CHRM3CACNA1CADRB1 | |
| SCHEMBL20373394 | 0.85 | ADRB2 (0.63) | ADRB2CHRM3ADRB1 | |
| SCHEMBL20373307 | 0.85 | ADRB2 (0.59) | ADRB2CHRM3ADRB1 | |
| SCHEMBL15771911 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C | |
| SCHEMBL20358347 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C | |
| SCHEMBL15772587 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C | |
| SCHEMBL19970944 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C | |
| SCHEMBL19970941 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C | |
| SCHEMBL15771912 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C | |
| SCHEMBL15771913 | 0.85 | CHRM3 (0.79) | ADRB2CHRM3CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2020-07-29 | — | — | EP | disclosed |
| EP-2928889-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-03-21 | — | — | EP | disclosed |