Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 5/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21915666 | 1.00 | NOTUM (0.38) | NOTUMHTR2COPRL1HPGDSLC6A2 | |
| SCHEMBL802760 | 0.92 | ESR2 (0.37) | NOTUMHTR2COPRL1HPGD | |
| SCHEMBL31026 | 0.92 | ESR2 (0.37) | NOTUMHTR2COPRL1HPGD | |
| SCHEMBL12716351 | 0.92 | OPRL1 (0.40) | NOTUMHTR2COPRL1HPGD | |
| SCHEMBL20312053 | 0.91 | OPRL1 (0.37) | NOTUMHTR2COPRL1HPGD | |
| SCHEMBL23624806 | 0.90 | NOTUM (0.34) | NOTUMHTR2COPRL1HPGD | |
| SCHEMBL12196538 | 0.90 | ESR2 (0.37) | NOTUMHTR2COPRL1HPGDSLC6A3 | |
| SCHEMBL17527749 | 0.90 | NOTUM (0.34) | NOTUMHTR2COPRL1HPGDHTR2A | |
| SCHEMBL10030799 | 0.90 | OPRL1 (0.38) | HTR2COPRL1HPGD | |
| SCHEMBL16768989 | 0.89 | OPRL1 (0.37) | NOTUMHTR2COPRL1HPGDSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064591-A1 | AZO DYE | MERCK PATENT GMBH (DE) | 2020-04-02 | — | — | WO | disclosed |
| EP-2997109-B1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DEVICE | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |