Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIEZO1 | Q92508 | 8/20 | 0.38 |
| ▸ | TERT | O14746 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17903550 | 0.75 | ALDH1A1 (0.38) | KDM4ESMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL19871032 | 0.67 | HCAR2 (0.40) | MAPTPOLB | |
| SCHEMBL19864340 | 0.65 | MAPT (0.49) | KDM4EMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19984824 | 0.65 | HDAC6 (0.34) | TERTKDM4E | |
| SCHEMBL19863311 | 0.65 | HCAR2 (0.39) | KDM4ENPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25209459 | 0.65 | SLC1A3 (0.53) | — | |
| SCHEMBL21690461 | 0.65 | SLC1A3 (0.53) | — | |
| SCHEMBL17477557 | 0.65 | SLC1A3 (0.53) | — | |
| SCHEMBL18078725 | 0.64 | CD274 (0.52) | KDM4EMEN1KMT2APOLB | |
| SCHEMBL19866357 | 0.64 | CD274 (0.52) | KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051255-A1 | CYCLIC SUBSTITUTED-1,3,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |