SCHEMBL19985400

SCHEMBL19985400

C=CCCC1CCC(c2ccc(-c3ccc(OCCCC)c(F)c3F)cc2)CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.35
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
CNR1 P21554 1/20 0.33
CYP2C9 P11712 2/20 0.33
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR2 Q92731 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
DGAT1 O75907 1/20 0.31
SOAT1 P35610 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
PDE4A P27815 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985419 0.97 GABRA1 (0.35) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL19985422 0.96 GABRA1 (0.35) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL19985403 0.96 GABRA1 (0.35) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL19985398 0.96 GABRA1 (0.35) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL19985401 0.96 GABRA1 (0.35) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL22277465 0.95 CNR2 (0.37) CNR2GABRA1GABRB2CNR1FFAR4
SCHEMBL19985396 0.95 GABRA1 (0.38) GABRA1GABRB2CYP2C9ALDH1A1LMNA
SCHEMBL8933627 0.93 CNR2 (0.35) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL19985437 0.93 GABRA1 (0.33) CNR2GABRA1GABRB2CNR1CYP2C9
SCHEMBL22277494 0.93 FFAR4 (0.39) CNR2GABRA1GABRB2CNR1PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed