Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19985426 | 0.91 | CYP2C9 (0.41) | ESR2ESR1CYP3A4CYP2C9FPR2 | |
| SCHEMBL19985431 | 0.89 | CYP2C9 (0.34) | ESR2CYP2C9DGAT1SOAT1ALDH1A1 | |
| SCHEMBL19985433 | 0.88 | CYP2C9 (0.34) | ESR2CYP2C9DGAT1SOAT1ALDH1A1 | |
| SCHEMBL19985418 | 0.87 | ESR2 (0.31) | ESR2ESR1CYP3A4CYP2C9FPR2 | |
| SCHEMBL15723057 | 0.87 | ESR2 (0.31) | ESR2ESR1CYP3A4CYP2C9FPR2 | |
| SCHEMBL19985452 | 0.87 | MAPT (0.34) | ESR2CYP3A4CYP2C9DGAT1SOAT1 | |
| SCHEMBL19985439 | 0.87 | MAPT (0.34) | ESR2CYP3A4CYP2C9DGAT1SOAT1 | |
| SCHEMBL19985454 | 0.87 | MAPT (0.34) | ESR2CYP3A4CYP2C9DGAT1SOAT1 | |
| SCHEMBL19985413 | 0.86 | ESR2 (0.39) | ESR2CYP3A4CYP2C9 | |
| SCHEMBL19985420 | 0.86 | HTR2C (0.38) | ESR2ESR1CYP3A4CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-20180079959-A1 | LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY | DIC CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |