SCHEMBL19985418

SCHEMBL19985418

C/C=C\Oc1ccc(-c2ccc(C3CCC(CC)CC3)cc2)c(F)c1F

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 2/20 0.31
ESR1 P03372 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
FPR2 P25090 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15723057 1.00 ESR2 (0.31) ESR2ESR1CYP3A4CYP2C9FPR2
SCHEMBL15723157 0.97
SCHEMBL15723058 0.91 CYP2C9 (0.40) ESR2ESR1CYP3A4CYP2C9
SCHEMBL19985427 0.91 CYP2C9 (0.40) ESR2ESR1CYP3A4CYP2C9
SCHEMBL8935775 0.90 FPR2 (0.32) FPR2
SCHEMBL19985429 0.89 CYP2C9 (0.34) ESR2CYP2C9
SCHEMBL15723059 0.89 CYP2C9 (0.34) ESR2CYP2C9
SCHEMBL15723063 0.88 FPR2 (0.31) FPR2
SCHEMBL19985435 0.88 CYP2C9 (0.33) ESR2CYP2C9
SCHEMBL15723160 0.88 CYP2C9 (0.38) ESR2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed