SCHEMBL19985428

SCHEMBL19985428

CC/C=C\Cc1ccc(-c2ccc(C3CCC(CCC)CC3)cc2)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 3/20 0.41
ALDH1A1 P00352 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MEN1 O00255 1/20 0.39
MAPK1 P28482 1/20 0.39
KMT2A Q03164 1/20 0.39
ESR2 Q92731 3/20 0.35
DGAT1 O75907 2/20 0.33
SOAT1 P35610 1/20 0.33
CYP3A4 P08684 2/20 0.31
ESR1 P03372 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985434 0.93 CYP2C9 (0.34) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL19985423 0.92 ESR2 (0.33) CYP2C9ALDH1A1ESR2DGAT1SOAT1
SCHEMBL19985447 0.91 MAPT (0.34) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL19985453 0.91 MAPT (0.34) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL19986347 0.86 CYP3A4 (0.40) CYP2C9ALDH1A1MAPTKMT2ADGAT1
SCHEMBL8933753 0.86 CYP3A4 (0.33) CYP2C9MAPTCYP3A4
SCHEMBL22881579 0.86 CYP2C9 (0.49) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL20273239 0.84 CYP2C9 (0.45) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL19985598 0.84 CYP2C9 (0.32) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL22277194 0.83 CYP2C9 (0.44) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed