SCHEMBL19985467

SCHEMBL19985467

CCOc1ccc(-c2ccc(C3CCC(CC)CC3)c(F)c2F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 4/20 0.36
ALOX5AP P20292 8/20 0.34
FEN1 P39748 8/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2B Q13224 1/20 0.34
KDM1A O60341 2/20 0.33
TRPV3 Q8NET8 1/20 0.33
FGFR1 P11362 1/20 0.33
FGFR2 P21802 1/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.32
BRD4 O60885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12716045 0.94 KDM1A (0.36) FPR2ALOX5APFEN1GRIN1GRIN2B
SCHEMBL9405701 0.94 KDM1A (0.36) FPR2ALOX5APFEN1GRIN1GRIN2B
SCHEMBL9405698 0.94 KDM1A (0.36) FPR2ALOX5APFEN1GRIN1GRIN2B
SCHEMBL10164629 0.93 FPR2 (0.36) FPR2ALOX5APFEN1GRIN1GRIN2B
SCHEMBL15381624 0.93 FPR2 (0.39) FPR2ALOX5APFEN1KDM1AFGFR1
SCHEMBL14922512 0.92 FPR2 (0.36) FPR2ALOX5APFEN1GRIN1GRIN2B
SCHEMBL19985468 0.91 FPR2 (0.38) FPR2ALOX5APFEN1
SCHEMBL15381722 0.90 ALOX5AP (0.40) FPR2ALOX5APFEN1
SCHEMBL15381684 0.90 ALOX5AP (0.40) FPR2ALOX5APFEN1
SCHEMBL9631105 0.90 KDM1A (0.34) FPR2ALOX5APFEN1GRIN1GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed