SCHEMBL1998547

SCHEMBL1998547

FC(=C(F)C(F)(F)Br)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1998546 1.00
SCHEMBL2000047 1.00
SCHEMBL8215521 0.89
SCHEMBL8215520 0.89
SCHEMBL333324 0.80
SCHEMBL2464884 0.80
SCHEMBL105368 0.80
SCHEMBL9500388 0.79
SCHEMBL9775378 0.79
Fluoride SCHEMBL20869507 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US claimed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US claimed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US claimed
CN-115536490-B Method for synthesizing tetrafluoro-bromobutene 中国矿业大学(北京) 2024-05-17 CN disclosed
US-11964938-B2 3-phenyl-4-hexynoic acid derivatives as GPR40 agonists CELON PHARMA S.A. (PL) 2024-04-23 US disclosed
EP-3737470-B9 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2024-03-13 EP disclosed
EP-3737470-B1 3-PHENYL-4-HEXYNOIC ACID DERIVATIVES AS GPR40 AGONISTS Celon Pharma Sa (PL) 2022-12-14 EP disclosed
US-8418530-B1 Compositions and methods for detecting leaks in HVAC/R systems MAINSTREAM ENGINEERING CORPORATION (US) 2013-04-16 US disclosed
US-7998916-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2011-08-16 US disclosed
US-7960331-B2 Replacement solvents having improved properties and methods of using the same GRZYLL LAWRENCE R 2011-06-14 US disclosed
US-7736537-B1 Replacement solvents having improved properties for refrigeration flushes MAINSTREAM ENGINEERING CORP. (US) 2010-06-15 US disclosed
US-7566409-B1 Replacement solvents having improved properties for refrigeration flushes MAINSTREAM ENGINEERING CORPORATION (US) 2009-07-28 US disclosed
US-20090026418-A1 Replacement Solvents Having Improved Properties and Methods of Using the Same MAINSTREAM ENGINEERING CORP. (US) 2009-01-29 US disclosed
US-20090005282-A1 Replacement Solvents Having Improved Properties and Methods of Using the Same MAINSTREAM ENGINEERING CORP. (US) 2009-01-01 US disclosed
US-7429557-B2 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORPORATION (US) 2008-09-30 US disclosed
US-20060166851-A1 Replacement solvents having improved properties and methods of using the same MAINSTREAM ENGINEERING CORP. 2006-07-27 US disclosed