SCHEMBL19985535

SCHEMBL19985535

C/C=C/C1CCC(c2ccc(-c3ccc(OC)c(F)c3F)c(F)c2F)CC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 11/20 0.33
FEN1 P39748 11/20 0.33
FPR2 P25090 5/20 0.33
PFKFB3 Q16875 1/20 0.30
PDE5A O76074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL803246 0.95 HTR2C (0.33) ALOX5APFEN1PDE5A
SCHEMBL4549750 0.95 HTR2C (0.33) ALOX5APFEN1PDE5A
SCHEMBL8935215 0.94 ALOX5AP (0.37) ALOX5APFEN1FPR2
SCHEMBL10030778 0.91 PDE5A (0.31) PDE5A
SCHEMBL4549760 0.91 PDE5A (0.31) PDE5A
SCHEMBL8962530 0.91 ALOX5AP (0.35) ALOX5APFEN1FPR2
SCHEMBL6457638 0.88 FPR2 (0.30) FPR2
SCHEMBL6457626 0.88 FPR2 (0.30) FPR2
SCHEMBL6457635 0.88 FPR2 (0.30) FPR2
SCHEMBL15723102 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed