SCHEMBL19985538

SCHEMBL19985538

C/C=C/C1CCC(c2ccc(-c3ccc(OCC)c(F)c3F)c(F)c2F)CC1

nearest known ligand 0.34

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 3/20 0.34
KDM1A O60341 2/20 0.31
FGFR1 P11362 1/20 0.31
FGFR2 P21802 1/20 0.31
ALOX5AP P20292 1/20 0.30
FEN1 P39748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15681359 0.95 KDM1A (0.33) KDM1A
SCHEMBL12716116 0.95 KDM1A (0.33) KDM1A
SCHEMBL21614463 0.95 KDM1A (0.33) KDM1A
SCHEMBL8935227 0.94 FPR2 (0.34) FPR2FGFR1FGFR2ALOX5APFEN1
SCHEMBL19985541 0.92 FPR2 (0.36) FPR2
SCHEMBL2215040 0.91 KDM1A (0.32) KDM1A
SCHEMBL15681328 0.91 KDM1A (0.32) KDM1A
SCHEMBL12511886 0.91 KDM1A (0.32) KDM1A
SCHEMBL8962677 0.91 FPR2 (0.33) FPR2FGFR1FGFR2ALOX5APFEN1
SCHEMBL19985540 0.91 SCN9A (0.34) FPR2ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed
US-20180079959-A1 LIQUID CRYSTAL ELEMENT WITH NEGATIVE DIELECTRIC ANISOTROPY DIC CORPORATION (JP) 2018-03-22 US disclosed