Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16074731 | 0.84 | MAPK1 (0.39) | TSHRCYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL12491994 | 0.81 | CYP1A2 (0.31) | CYP1A2CYP3A4CYP2C9HIF1AMAPK1 | |
| SCHEMBL15892039 | 0.80 | TSHR (0.38) | TSHR | |
| SCHEMBL5907128 | 0.80 | TSHR (0.38) | TSHR | |
| SCHEMBL7875262 | 0.79 | — | — | |
| SCHEMBL10749806 | 0.78 | TRPA1 (0.35) | TSHR | |
| SCHEMBL23856094 | 0.77 | MAPK1 (0.35) | TSHRCYP1A2CYP3A4CYP2C9HIF1A | |
| SCHEMBL1005408 | 0.77 | — | — | |
| SCHEMBL16074697 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL1191515 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180079839-A1 | HIGH ALCOHOL TOLERANT COPOLYMERS AND TERPOLYMERS BASED ON POLYVINYL ALCOHOLS | SUN CHEMICAL CORPORATION (US) | 2018-03-22 | — | — | US | disclosed |