SCHEMBL19985916

SCHEMBL19985916

c1ccc(-n2c3ccccc3c3cc(-c4ccc(-n5c6ccccc6c6c7c8ccccc8c8ccccc8c7c7c8ccccc8sc7c65)cc4)ccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HDAC4 P56524 1/20 0.33
HSD17B10 Q99714 1/20 0.32
TSPO P30536 1/20 0.31
LIMK1 P53667 1/20 0.31
PTGER4 P35408 1/20 0.31
MAPT P10636 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985941 0.94 KDM4E (0.38) KDM4EATML3MBTL1HSD17B10TSPO
SCHEMBL19985942 0.93 KDM4E (0.40) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL19985940 0.92 ATM (0.43) KDM4EATML3MBTL1HSD17B10MAPT
SCHEMBL19985908 0.91 TP53 (0.32) KDM4EATML3MBTL1LIMK1MAPT
SCHEMBL19985904 0.90 KDM4E (0.33) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL19985919 0.90 L3MBTL1 (0.37) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL19985970 0.90 L3MBTL1 (0.37) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL18748659 0.89 KDM4E (0.38) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL18748705 0.89 KDM4E (0.38) KDM4EATML3MBTL1HDAC4HSD17B10
SCHEMBL18748619 0.89 KDM4E (0.40) KDM4EATML3MBTL1HDAC4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed