SCHEMBL19985929

SCHEMBL19985929

c1ccc2c(c1)ccc1ccc(-n3c4ccccc4c4c5c6ccccc6c6ccccc6c5c5c6ccccc6sc5c43)cc12

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 4/20 0.33
ALDH1A1 P00352 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP1B1 Q16678 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 4/20 0.32
RXFP1 Q9HBX9 1/20 0.32
HPRT1 P00492 1/20 0.31
PMM2 O15305 1/20 0.31
MPI P34949 1/20 0.31
PHOSPHO1 Q8TCT1 1/20 0.31
NQO1 P15559 1/20 0.31
NQO2 P16083 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19985912 0.94 HPRT1 (0.33) TP53ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL19985921 0.91 PMM2 (0.39) TP53ALDH1A1HSD17B10MAPTRXFP1
SCHEMBL19985906 0.91 TP53 (0.30) TP53
SCHEMBL19985972 0.90 TP53 (0.35) TP53ALDH1A1MAPTRXFP1
SCHEMBL19985923 0.89 MAPT (0.33) TP53CYP1B1MAPTRXFP1
SCHEMBL18748639 0.88 CYP1A2 (0.34) TP53ALDH1A1HIF1ACYP1B1HSD17B10
SCHEMBL19985960 0.88 GPR3 (0.36) TP53ALDH1A1MAPTRXFP1CYP1A2
SCHEMBL19985924 0.88 PDPK1 (0.32) HPRT1NQO1NQO2CYP1A2
SCHEMBL19985931 0.86 MAPT (0.33) TP53CYP1B1MAPTRXFP1CYP1A2
SCHEMBL19985946 0.85 MAPT (0.38) TP53ALDH1A1MAPTRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083202-A1 COMPOUND FOR ORGANIC OPTOELECTRIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRIC DEVICE AND ORGANIC OPTOELECTRIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-03-22 US disclosed